This project aims to create a new point-of-care device based
on MEMS-based resonant transducers integrated with microfluidic sample
handling to develop a portable, low-power, potentially disposable
device for near-patient monitoring. The project will involve a
research collaboration between groups based at the Department of
Anaesthesia, Addenbrookes' Hospital and in the Nanoscience Centre in
the Department of Engineering. The underlying physical basis for the
detection principle builds upon previous work in the Seshia group in
the area of MEMS-based biosensors. These devices are constructed from
thin silicon films patterned and etched using standard semiconductor
foundry processing to create freestanding mechanical structures that
can be co-integrated together with microfluidic sample handling. These
devices have demonstrated high sensitivity to visco-elastic loading
due to the reduced dimensional scale and can be fully electrically
interrogated in liquid environments.
| Dr. Ashwin Seshia |
Department of Engineering |
| Prof. David Menon |
Department of Anaesthesia |
| Dr. Ari Ercole |
Department of Anaesthesia |
